Publications
Lactoferrin derived anti-scarring peptide
Håkansson J1, Mahlapuu M, Ekström L, Olmarker K, Wiig M., Effect of lactoferrin peptide (PXL01) on rabbit digit mobility after flexor tendon repair. Hand Surg Am. 2012 (12):2519-25.
https://journals.sagepub.com/doi/10.1177/1753193411410823
Nilsson E1, Björn C, Sjöstrand V, Lindgren K, Münnich M, Mattsby-Baltzer I, Ivarsson ML, Olmarker K, Mahlapuu M., A novel polypeptide derived from human lactoferrin in sodium hyaluronate prevents postsurgical adhesion formation in the rat. Ann Surg
. 2009,250(6):1021-8.
https://www.ncbi.nlm.nih.gov/pubmed/19953722
Wiig ME, Dahlin LB, Fridén J, Hagberg L, Larsen SE, Wiklund K, Mahlapuu M. , PXL01 in sodium hyaluronate for improvement of hand recovery after flexor tendon repair surgery: randomized controlled trial. PLoS One. 2014 23;9(10):e110735. doi: 10.1371/journal.pone.0110735. eCollection 2014.
https://lucris.lub.lu.se/ws/files/3843122/7525885
Scarring and adhesions
Dermal Scarring
Finnerty CC, Jeschke MG, Branski LK, Barret JP, Dziewulski P, Herndon DN., Hypertrophic scarring: the greatest unmet challenge after burn injury. Lancet. 2016 ;388(10052):1427-1436. Review
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)31406-4/fulltext
Lee HJ, Jang YJ., Recent Understandings of Biology, Prophylaxis and Treatment Strategies for Hypertrophic Scars and Keloids. Int J Mol Sci. 2018 9(3). pii: E711. Review
https://www.researchgate.net/publication/323529902_Recent_Understandings_of_Biology_Prophylaxis
Li-Tsang CW, Lau JC, Chan CC. Prevalence of hypertrophic scar formation and its characteristics among the Chinese population. Burns. 2005,31(5):610-6
https://www.ncbi.nlm.nih.gov/pubmed/15993306
Marshall CD, Hu MS, Leavitt T, Barnes LA, Lorenz HP, Longaker MT., Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions., Adv Wound Care (New Rochelle). 2018 7(2):29-45.
https://www.liebertpub.com/doi/pdf/10.1089/wound.2018.0787
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Post-operative adhesions
Awonuga AO, Fletcher NM, Saed GM, Diamond MP., Postoperative adhesion development following cesarean and open intra-abdominal gynecological operations: a review. Reprod Sci. 2011, (12):1166-85. Review
https://reference.medscape.com/medline/abstract/21775773
Baber Z, Erde MA, Failed back surgery syndrome: current perspectives. J Pain Research, 2016; 9 : 979—987
Lue JR , Boyd LS, Diamond MP, Pelvic Adhesive Disease: Current Approaches to Management, J Womens Health Issues Care 2014, ;44(3):405-20. . Review.
Moris D, Chakedis J, Rahnemai-Azar AA, Wilson A, Hennessy MM, Athanasiou A, . Postoperative Abdominal Adhesions: Clinical Significance and Advances in Prevention and Management, Journal of Gastrointestinal Surgery, 2017, 10: 1713–1722
https://link.springer.com/article/10.1007%2Fs11605-017-3488-9
Okabayashi K, Ashrafian H, Zacharakis E, Hasegawa H, Kitagawa Y, Athanasiou T, Darzi A., Adhesions after abdominal surgery: a systematic review of the incidence, distribution and severity. Surg Today, 2014, 44(3):405-20
Gene therapy
Gorell E, Nguyen N, Lane A, Siprashvili Z., Gene therapy for skin diseases., Cold Spring Harb Perspect Med. 2014 Apr 1;4(4):a015149. doi: 10.1101/cshperspect.a015149. Review.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968787/pdf/cshperspectmed-SKN-a015149.pdf
Naso MF, Tomkowicz B, Perry WL 3rd, Strohl WR., Adeno-Associated Virus (AAV) as a Vector for Gene Therapy. BioDrugs. 2017, (4):317-334. doi: 10.1007/s40259-017-0234-5. Review.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548848/pdf/40259_2017_Article_234.pdf
Van Leshout LP, Domm JN, Rindler TN, Frost KL, Sorensen DL, Medina SJ, Booth SA, Bridges JP, and Wootton SK. A Novel Triple-Mutant AAV6 Capsid Induces Rapid and Potent Transgene Expression in the Muscle and Respiratory Tract of Mice. Mol Ther Methods Clin Dev. 2018 Jun 15; 9: 323–329.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054702/pdf/main.pdf