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Proof of Anti-scarring effect of lactoferrin derivate

 

Preclinical 

Annals of Surgery. 250(6):1021-1028, 20 

 

https://insights.ovid.com/pubmed?pmid=19953722                          

 

A Novel Polypeptide Derived From Human Lactoferrin in Sodium Hyaluronate Prevents Postsurgical Adhesion Formation in the Rat

Elin Nilsson; Camilla Björn; Veronika Sjöstrand; Kerstin Lindgren; Mattias Münnich; Inger Mattsby-Baltzer; Marie-Louise Ivarsson; Kjell Olmarker; Margit Mahlapuu 

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 More than 50-70 percent reduction of scarring with

formulations of lactoferrin derivate (PXL-01)

Gold standard multiple abrasion model in the rat

Clinical 

PLOSOne 9(10) : e 110735 October 23, 2014

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207831/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207831/

PXL01 in Sodium Hyaluronate for Improvement of Hand Recovery after Flexor Tendon Repair Surgery: Randomized Controlled Trial

Monica E. Wiig , Lars B. Dahlin, Jan Fridén, Lars Hagberg, Sören E. Larsen, Kerstin Wiklund,

Margit Mahlapuu 

In a large multi center study in 138 patients anti-scarring peptide PXL-01 (enserptide)  caused  40-60 percent improvement of scarring related dysfunction  after hand surgery with repair of  raptured tendon .

 

Scarring and adhesions may reduce the mobility of fingers which compromises hand function and Activities of Daily Life